2010/09/20

Amixide

Composition, structure and packing

Tablets are round, peach-colored, with a pitch scored one hand, film-coated.

1 tab.

amitriptyline hydrochloride 12.5 mg.

chlordiazepoxide 5 mg.

Excipients: lactose, starch, sodium edetate disubstituted, microcrystalline cellulose, colloidal silicon dioxide, sodium lauryl sulfate, sodium methylparaben, talc, magnesium stearate, krospovidon, eudrazhit E100B, titanium dioxide, quinoline yellow, indigo, polyethylene glycol 6000.

Tablets are round, light green, with a pitch scored one hand, film-coated.

1 tab.

Amitriptyline Hydrochloride 25 mg.

chlordiazepoxide 5 mg.

Excipients: lactose, starch, sodium edetate disubstituted, microcrystalline cellulose, colloidal silicon dioxide, sodium lauryl sulfate, sodium methylparaben, talc, magnesium stearate, krospovidon, eudrazhit E100B, titanium dioxide, quinoline yellow, indigo, polyethylene glycol 6000.

Tablets are round, blue, with a pitch scored one hand, film-coated.

1 tab.

Amitriptyline Hydrochloride 25 mg.

chlordiazepoxide 10 mg.

Excipients: lactose, starch, sodium edetate disubstituted, microcrystalline cellulose, colloidal silicon dioxide, sodium lauryl sulfate, sodium methylparaben, talc, magnesium stearate, krospovidon, eudrazhit E100B, titanium dioxide, quinoline yellow, indigo, polyethylene glycol 6000.

Clinico-pharmacological group: drug with antidepressant and anxiolytic effects.

Pharmacological action

Combination drug whose action is due to its constituent components, has anti-depressant, anxiolytic effects.

The mechanism of action is based on the simultaneous effect of antidepressant on the reuptake of norepinephrine and serotonin in the CNS and anxiolytic - the limbic system, responsible for the emotional state.

Statement
depression of various origin, accompanied by anxiety.

Dosage regimen

Drugs are taken inside, the initial dose for adults - 1 tablet 2-3 times daily, with an inadequate expression of the effect of daily dose increased to 6 tablets.

Side effect

Confusion, disorientation, ataxia, tremor, peripheral neuropathy, hallucinations, dysarthria, reduced ability to concentrate, anxiety, insomnia, motor excitation, drowsiness, dizziness, headache, increased secretion of ADH, tinnitus, epileptic syndrome, arrhythmias, decrease blood pressure, tachycardia, palpitations, urinary retention, blurred vision, paresis of accommodation, increased intraocular pressure, mydriasis, dry mouth, dyspepsia, weight gain (edema) of testicles, gynecomastia, glandular enlargement, galactorrhea, alopecia, weight gain, allergic reactions

Contraindications
hypersensitivity
epilepsy (including history),
myocardial infarction (acute phase),
receiving MAO inhibitors,
pregnancy
lactation,
prostate hyperplasia,
liver and / or kidney failure.

C carefully. Angle-closure glaucoma, angina, thyrotoxicosis.

Pregnancy and lactation

Use of the drug is contraindicated

Cautions

During the drug treatment did not appoint electroconvulsive therapy.

During the period of treatment must be careful when driving and other lesson potentially dangerous activities which require high concentration and speed of psychomotor reactions.

Drug Interactions

Incompatible with antipsychotic drugs, holinoblokatorami, ethanol, MAO inhibitors.