2010/09/20

Aminosteril Ke

Composition, structure and packing

Solution for infusion 10% - 1 liter.
L-leucine 7.06 g;
L-isoleucine 4.67 g;
monogidrohlorid lysine 7.46 g, which corresponds to the content of L-lysine 5.97 g;
L-methionine 4.1 g;
L-phenylalanine 4.82 g;
L-threonine, 4.21 g;
L-tryptophan 1.82 g;
L-Valine 5.92 g;
L-arginine 10.64 g;
L-histidine, 2.88 g;
glycine, 15.95 g;
L-alanine 15 g;
L-proline 15 g;
L-malic acid 8.08 g;
Na + 30 mM;
K + 20 mmol;
Mg2 + 5 mmol;
Cl-60 mmol;
total nitrogen 16 mg / L;
osmolarity 1048 mOsm / liter.

Clinico-pharmacological group: The preparation for parenteral nutrition - a solution of amino acids and electrolytes.

Pharmacological action

The preparation for parenteral nutrition. Amino acids contained in the product Aminosteril CIs are in the L-form that allows their direct involvement in the biosynthesis of proteins and achieve a positive nitrogen balance in parenteral nutrition.

The product contains all eight essential amino acids and amino acids. Malic acid is a source of energy for the synthesis of urea. Na +, K +, Mg2 +, Cl-are key elements in the maintenance of electrolyte and acid-base balance in the body.

Pharmacokinetics

Data on the pharmacokinetics Aminosteril CIs are not provided.

Statement
partial parenteral nutrition;
total parenteral nutrition (in conjunction with the introduction of carbohydrate and fat emulsions as a source of energy).

Dosage regimen

The drug is introduced into / in the infusion dose of 1.3 ml / kg body weight / h (25-30 drops / min per 70 kg body weight). The maximum daily dose: 1000 ml per 70 kg body weight, which corresponds to approximately 16 g total nitrogen.

Side effect

Perhaps: hypersensitivity reactions.

Contraindications
metabolism of amino acids;
renal dysfunction;
hyperkalaemia;
Chronic heart failure in the stage of decompensation.

Pregnancy and lactation

No data on the possible use of the drug during pregnancy and lactation.

Application for violations of renal function

Contraindicated in renal events.

Cautions

The simultaneous introduction of solutions of carbohydrates and fat emulsions. Note that the treatment with the use of parenteral nutrition should not exceed the volume of 40 ml / kg / day total amount of fluid that is introduced to the patient.

When odnovremennnom introduction of other drugs should take into account their osmolarity.

Overdose

Data on drug overdose Aminosteril CIs are not provided.

Drug Interactions

Currently, drug interactions drug Aminosteril CI is not described.

Terms and Conditions of storage

The drug should be stored in a dark place at temperatures not above 25 ° C.

Shelf life - 2 years. Use only clear solutions in intact vials.