Composition, structure and packing

Tablets, film-coated white to white with a yellowish tint, with splashes, oval, biconvex, engraved with "ARTRA" on the one hand, with a specific smell.

1 tab. chondroitin sulfate sodium 500 mg of glucosamine hydrochloride 500 mg.

Excipients: calcium sulfate, disodium, microcrystalline cellulose, sodium croscarmellose, stearic acid, magnesium stearate.

The composition of the shell: hydroxypropylmethylcellulose, titanium dioxide (E171), triacetin.

Clinico-pharmacological group: The drug that stimulates the regeneration of cartilage tissue.

Pharmacological action

Stimulator of regeneration of cartilage tissue. Glucosamine and chondroitin sulfate sodium involved in the biosynthesis of connective tissue, helping to prevent the destruction processes of cartilage, stimulating the regeneration of tissue. Introduction of exogenous glucosamine increases production of cartilage matrix and provides nonspecific protection, including of NSAIDs and the SCS.

The drug has mild anti-inflammatory action. Chondroitin sulfate sodium, regardless of whether it is absorbed in intact form or as individual components, serves as an additional substrate for the formation of healthy cartilage matrix.

It stimulates the formation of proteoglycans and collagen type II, and also protects the cartilage matrix by enzymatic cleavage (by suppressing the activity of hyaluronidase) and from the damaging effect of free radicals, maintains the viscosity of synovial fluid, stimulates cartilage repair mechanisms and inhibits the activity of those enzymes (elastase, hyaluronidase), which break down cartilage.

In the treatment of osteoarthritis relieves symptoms of the disease and reduces the need for NSAIDs.



Bioavailability of glucosamine ingestion - 25% (due to the effect of "first pass" through the liver). Bioavailability of chondroitin sulfate - 13%.


Distributed in the tissues: highest concentrations of glucosamine found in the liver, kidneys and articular cartilage. About 30% of applied dose long persist in bone and muscle tissue.


Glucosamine is derived mainly from the urine in unchanged form, in part - with the feces. T1 / 2 of glucosamine - 68 pm

osteoarthritis of peripheral joints and spine.

Dosage regimen

Into adults and children over 15 years appoint 1 tab. 2 times / day during the first three weeks of 1 tablet. 1 time per day over the next weeks and months. Sustained therapeutic effect is achieved while taking the drug for at least 6 months.

Side effect
On the part of the digestive system: lung dysfunction GIT - epigastric pain, flatulence, diarrhea, constipation (due to the action of glucosamine).
From the side of the central nervous system: dizziness (due to the action of glucosamine).
Other: allergic reactions (caused by the action of glucosamine and chondroitin sulfate).

marked impairment of renal function;
Hypersensitivity to the drug's components.

Precautions are used for bleeding or bleeding tendency, bronchial asthma, diabetes.

Pregnancy and lactation

Artro drug is not recommended during pregnancy and during lactation.

Application for violations of renal function

The drug is contraindicated in disturbancies renal function.


Use in Pediatrics

Clinical data on efficacy and safety of the drug arthritis in children aged under 15 years of absence.


So far, cases of overdosing Artro not reported.

Treatment: gastric lavage, symptomatic therapy.

Drug Interactions

When applied simultaneously increases the effects of anticoagulants and antiplatelet agents. Increases absorption of tetracycline reduces the effect of semisynthetic penicillins. The product is compatible with the SCS.

Terms and Conditions of storage

The drug should be stored out of reach of children, dry place at temperatures from 10 ° to 30 ° C. Shelf life - 5 years.