Aprofene tablets 0.025 g

Method of production - Tablets 25 mg

Pharmacotherapeutic group - m-and n-holinoblokator

Pharmacological action
m-and n-anticholinergic
N-central anticholinergic
m-central anticholinergic

Ingredients - APROFAM 25 mg

Arteritis unspecified
Pain in the abdomen and pelvis
Diseases of the gall bladder, biliary tract and pancreas
Stones of bile duct with cholecystitis
Renal colic, unspecified
Acute cholecystitis
Vascular headache, not elsewhere classified
Vascular diseases of the intestine
Vascular disease intestine unspecified
Chronic cholecystitis
Chronic vascular disease
Cholecystitis, unspecified
Other diseases of intestines
Other and unspecified abdominal pain
Other lesions of arteries and arterioles
Other headache syndromes
Other forms of cholecystitis
Gastric ulcer

The composition of the components


The white crystalline powder, easily soluble in water and alcohol. Aqueous solutions (pH 3,7-4,7), sterilized at 100 SDG for 30 min.


Has the peripheral and central m-and n-holinoliticheskoe action. In peripheral cholinolytic effect is more active than spazmolitin. Dilates coronary vessels, and in this respect he is more active than spazmolitin and papaverine. It is toning and strengthening the uterine contractions.


Apply with spasms of the abdominal cavity (spastic colitis, cholecystitis, renal and hepatic colic, peptic ulcer) and spasm of vessels (endarteritis, spasms of cerebral vessels). In obstetric practice, sometimes used to stimulate labor: while increasing uterine APROFAM reduces spasm of the pharynx and promotes more rapid disclosure of the cervix in the first stage of labor.

Dosage regimen

Assign inside after eating at a dose of 0,025 g of 2 - 4 times a day. Higher doses for adults inside; single 0.03 grams daily 0.1 g. When the application should individually select the dose.

Side effects

In case of overdose can appear dizziness, headache, feeling of intoxication (in conjunction with central action), dry mouth (due to peripheral cholinolytic action), breach of accommodation. By providing an irritating effect on the gastric mucosa, spazmolitin may cause dyspeptic symptoms. The feeling of intoxication and dizziness can prevent or reduce the appointment of caffeine (0,1-0,2 g caffeine-sodium benzoate inside or 1 ml of 20% solution under the skin).




APROFAM should not take before and during transport drivers and others whose profession requires quick mental and physical reactions.