2010/09/21

Artra Chondroitin

Composition, structure and packing

Capsules are hard gelatin, opaque, from white to almost white; the contents of capsules - powder from white to almost white; exception of specific smell.

1 capsule. chondroitin sulfate sodium 250 mg - 500 mg - 750 mg.

Excipients: rice flour, silicon dioxide, magnesium stearate. The composition of the shell capsules: gelatin, titanium dioxide.

Clinico-pharmacological group: The drug that stimulates the regeneration of cartilage tissue.

Pharmacological action

Stimulator of regeneration of cartilage tissue. Influences on exchange processes in hyaline and fibrous cartilage, stimulates the biosynthesis of glycosaminoglycans. Slows bone resorption and reduces calcium loss, accelerates restoration of bone tissue.

Reduces degenerative changes and promotes the restoration of cartilage of joints, relieves pain in joints and spine, increases joint mobility, is involved in the formation of bone, ligament, maintaining firmness and elasticity of the vascular wall.

In the treatment of osteoarthritis relieves symptoms of the disease and reduces the need for NSAIDs. Slows bone resorption and reduces calcium loss, accelerates restoration of bone tissue. The therapeutic effect persists for a long time after treatment.

Pharmacokinetics

Absorption and distribution

Once inside more than 70% of chondroitin sulfate is absorbed from the gastrointestinal tract. Bioavailability is 13%. For a single ingestion of high therapeutic dose Cmax in plasma observed after 3-4 h, in the synovial fluid after 4-5 hours absorbed from the gastrointestinal tract drug accumulates in the synovial fluid.

Withdrawal

We derive the kidneys.

Statement
osteoarthritis of peripheral joints;
osteochondrosis of the spine.

Dosage regimen

The drug is prescribed into adults. Capsules 250 mg - 2 capsules. 2 times / day.

Capsules 500 mg - 1 capsule. 2 times / day.

Capsules 750 mg - 1-2 kaps. / day. The recommended duration of the initial course of treatment - 6 months. The period of the drug after its cancellation - 3-5 months.

Duration of repeated courses of treatment is established by a doctor individually.

Side effect

Rare: allergic reaction.

Contraindications
Hypersensitivity to the drug's components.

Pregnancy and lactation

Not advisable to appoint during pregnancy and lactation (breastfeeding) in the absence of clinical experience in this patient.

Cautions

Precautions should be prescribed to patients with bleeding, as well as patients with a tendency to bleeding.

Overdose

Cases of overdose are unknown.

Treatment: gastric lavage, the holding of symptomatic therapy.

Drug Interactions

With simultaneous application may gain indirect action of anticoagulants, antiplatelet agents, fibrinolytics. The product is compatible with NSAIDs and SCS.

Terms and Conditions of storage

The drug should be stored out of reach of children, dry place at temperatures from 10 ° to 30 ° C. Shelf life - 3 years.