Composition, structure and packing

Ointment for external use of white to slightly yellowish, uniform consistency, with the smell of methyl salicylate. 1 g of bee venom 30 mcg methyl salicylate 100 mg ALLYL ISOTHIOCYANATE 10 mg.

Excipients: tsetilstearilovy alcohol, petrolatum, sodium lauryl sulfate, water.

Clinico-pharmacological group: preparation of local irritant and analgesic effect.

Pharmacological action

Combined medication on the basis of bee venom for outdoor use. Provides local irritant effect due to stimulation of peripheral nerves.

Has a direct vasodilator action, which leads to better tissue oxygen supply, causing pain accelerates the decomposition products of metabolism. Methyl salicylate and ALLYL ISOTHIOCYANATE cause flushing of the skin, have analgesic and warming effects. Apizartron helps enhance metabolism, increase elasticity of the connective tissue and muscles, a decrease in muscle tone.

The action develops within a few minutes after applying the product to affected area.


Data on the pharmacokinetics Apizartron not available.

diseases of musculoskeletal system (osteoarthritis, rheumatoid lesion of soft tissues);
arthralgia (including rheumatic diseases of the joints);
myalgia (including related overstress);
neuralgia (including neuritis, sciatica);
violations of peripheral circulation;
pain syndrome with mild lesions of muscles, tendons, ligaments, with bruises and sprains;
to warm up muscles before and during sporting loads.

Dosage regimen

Strip of ointment 3-5 cm in length assigned to work in the field of damage to the layer thickness of about 1 mm and left for 2-3 minutes (depending on the reactivity of the organism) until you see the reaction on the application of the drug (redness, a feeling of warmth). Then slowly and intensely rub ointment into the skin.

To enhance the therapeutic effect is recommended to keep the treated area of the body in warmth. Typically, ointment Apizartron apply 2-3 times per day until disappearance of symptoms.

After applying Apizartrona hands should be thoroughly cleaned with soap and water.

Side effect

Allergic reactions: seldom - skin rash, itching in the area of application of ointment.

chronic renal failure severe;
severe liver disease;
inhibition of bone marrow hematopoiesis;
mental illness;
acute arthritis
Children under 12 years
Hypersensitivity to bee venom, salicylates, izotiatsianatam.

Pregnancy and lactation

Do not use ointments Apizartron during pregnancy and lactation (breastfeeding).

Application for violations of liver function

Contraindicated in severe liver diseases.

Application for violations of renal function

Contraindicated in patients with chronic renal failure and severe.


The drug should not apply to damaged and irritated skin, as well as areas affected by skin disease. In patients with renal insufficiency Apizartron should not be applied over a large surface of the skin for a long time.

Avoid contact with eyes, ointments, mucous membranes and open wounds.


Data on drug overdose Apizartron not available.

Drug Interactions

Drug Interactions drug Apizartron not described.

Terms and Conditions of storage

The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 3 years. The drug should not be used after the expiry date stated on the packaging