2010/09/17

Alvedon

White or white with cream or pink crystalline powder. Easily soluble in alcohol, insoluble in water.

Paracetamol is chemically similar to phenacetin. It is the main metabolite, quickly formed in the body when taking phenacetin, apparently, causes analgesic effect of the latter. In analgesic activity paracetamol did not significantly differ from phenacetin; like phenacetin, he has a weak anti-inflammatory activity. The main advantages of paracetamol are less toxic, less ability to induce the formation of methemoglobin. However, this drug can also cause side effects, with prolonged use, especially in large doses, paracetamol may have a nephrotoxic, hepatotoxic effect.

Paracetamol is absorbed in the upper intestine, metabolized in the liver, released mainly by the kidneys.
Indications are the same as for amidopirina and phenacetin.

Dosage regimen

Doses for adults 0 2 - 0, 4 g per reception 2 - 3 times a day.

Higher doses for adults inside: single 0, 5 grams daily of 1, 5 PM

Children aged 6 to 12 months prescribed by 0, 025 - 0, 05 g, 2 - 5 years - 0 1 - 0, 15 g, 6 - 12 years - 0 15 - 0, 25 g per reception 2 - 3 times a day.

In the application of paracetamol should monitor liver function, the state of the hematopoietic system, possible allergic reactions.

Substance

Powder and tablets at 0, 2

Storage: List B. The well ukuporennoy packaging keeps from the world: pills - in a dark place.

Recently, in connection with the limitation of amidopirina and phenacetin were relatively extensive use of paracetamol and paracetamol-containing combination dosage forms (in combination with acetylsalicylic acid, analginom, caffeine, codeine, etc.).

Abroad, paracetamol (Panadol, panadon) is available in various dosage forms: tablets, capsules, medicine, syrup, effervescent, powders. There are a number of combined dosage forms containing acetaminophen in combination with caffeine, codeine and other drugs;

In the Republic of Korea issued a drug Coolpain-S (kulpeyn-S; kulpan-C) - tablets containing 0, 5 g of paracetamol and 0, 25 g of methionine.

No comments:

Post a Comment