2010/09/17

Actipol

Composition, structure and packing

Solution for injection and instillation

1 ml. para-aminobenzoic acid 70 mg

1 amp. para-aminobenzoic acid 140 mg

Excipients: Water d /, and sodium chloride

Clinico-pharmacological group: Antiviral and immunomodulatory drug for local use in ophthalmology. Inductor synthesis of interferon

Pharmacological action

Antivirus and immunomodulatory drug for local use. Inductor synthesis of endogenous interferon. Provides antioxidant, immunomodulating and radioprotective effect, accelerates regeneration of the cornea.

Pharmacokinetics

When used topically in ophthalmic practice (regardless of route of administration) of para-aminobenzoic acid is rapidly absorbed.

Statement
herpetic eye damage caused by the virus Herpes simplex, Varicella zoster;
adenoviral eye disease (conjunctivitis, keratitis, keratouveit).

Dosage regimen

The drug is prescribed in the form of instillation into the conjunctival sac of 1-2 drops 3-8 times, as well as subkonyunktivalnyh and parabulbarnyh injection of 0.3-0.5 ml (3-15 injections per course of treatment).

In the treatment of superficial forms of herpetic keratitis Aktipol used in the form of injections 1 time in 2-3 days in combination with the instillation of the drug 4-8 times / Multiplicity introduction depends on the clinical course of disease.

With deep forms of herpetic keratitis in the background instillyatsionnogo of the drug injection Aktipola at the beginning of therapy on a daily basis, then 1 every 2-3 days. After reaching the clinical effect of instillation of the drug should continue to 3 within 7-10 days.

Side effect

Local reactions: seldom - hyperemia of the conjunctiva.

Contraindications

Currently contraindications are not installed.

Pregnancy and lactation

Adequate and strictly controlled clinical trials the safety of the drug during pregnancy and lactation was conducted. In experimental studies found that the drug does not have teratogenic, mutagenic and embryotoxic action.

Cautions

You should not assign Aktipol simultaneously with sulfanilamide preparations.

Overdose

In case of accidental ingestion of the drug Aktipol risk of unwanted side effects is absent.

Drug Interactions

When applied simultaneously with the nucleoside reverse transcriptase inhibitors (acyclovir, ganciclovir, ARA-A, TFT) and antibiotics there is a growing therapeutic action Aktipola.

Terms and Conditions of storage

The drug should be stored in the dark place. Shelf life - 2 years.

After opening the ampoule the drug can be used within 24 hours