Alex Plus

Composition, structure and packing

Pastilles round, flat, orange-brown on each side of which is engraved "Alex".

A troche dextromethorphan hydrobromide 2 mg Turpin Hydrate 2 mg levomentol 750 mcg.

Excipients: sucrose, dextrose fluid, sodium glitsirrizinat, caramel coloring, coloring sunset yellow, lemon-oil concentrated, ginger oil, tartaric acid, sodium chloride, metilgidroksibenzoat, propilgidroksibenzoat, solid paraffin, magnesium stearate, calcium carbonate, carnauba wax, paraffin, liquid, talc purified, purified water.

Clinico-pharmacological group: preparation with antitussive and expectorant action.

Pharmacological action

Antitussive drug with expectorant and bronhospazmoliticheskim action. Dextromethorphan increases the sensitivity threshold of the cough center of the medulla oblongata, while not causing the oppression of the respiratory center, has antitussive and sedative effect, no tolerance effect, has no analgesic effect.

Turpin Hydrate has an expectorant effect, increases the secretory function of epithelial glands of the respiratory tract, increases the amount of secretion and reduces the viscosity of allocated secret. Levomentol a moderate spasmolytic effect, facilitates the patient with rhinitis, pharyngitis, laryngitis and bronchitis.

After taking the drug antitussive effect develops after 30 minutes and lasts for 6 hours



After taking the drug dextromethorphan is completely absorbed from the gastrointestinal tract. Dextromethorphan Cmax in plasma achieved in 2 hours Turpin hydrate is rapidly absorbed from the gastrointestinal tract after ingestion.

Metabolism and excretion

Dextromethorphan biotransformiruetsya in the liver. Up to 45% of dextromethorphan appears kidneys, while there is considerable individual variability in rates of excretion of individual metabolites. Turpin Hydrate circulates in the blood unchanged and is discharged through the respiratory tract, urine and sweat, which he attaches a specific smell. Part of the drug in the body is subjected to oxidation and is excreted in the urine in the form of phenols with glucuronic acid.


Acute and chronic respiratory diseases, accompanied by a dry irritating cough.

Dosage regimen

Adults recommend 2-5 pellets into 3-4 times per day, maximum daily dose is 20 pellets. In children, dosage depends on the age of the patient.

Children aged 4 to 6 years drug appoint a pastilles 3-4 times per day, maximum dose - 4 lozenges per day. Children aged 7 to 12 years prescribed 1-2 pastilles 3-4 times per day, maximum daily dose of 8 pellets. Pastilles should resolve to complete dissolution.

Side effect

Rare: drowsiness, nausea, dizziness, pruritus, urticaria.

acute attack of bronchial asthma;
Lactation (breastfeeding);
Children under 4 years;
Hypersensitivity to the drug's components.

Pregnancy and lactation

Alex Plus drug is contraindicated during pregnancy and lactation. Application for violations of liver function should be carefully appoint Alex Plus patients with impaired liver function.


Caution appoint Alex Plus patients with impaired liver function.

Effects on ability to drive vehicles and management mechanisms

During the period of the drug should refrain from classes of potentially hazardous activities that require attention and quickness of psychomotor reactions.


Symptoms: jitters, dizziness, respiratory depression, lowering blood pressure, tachycardia, dyspeptic disorders.

Treatment: If necessary, a symptomatic therapy, mechanical ventilation. With a very serious overdose is possible to use an antidote naloxone.

Drug Interactions

At simultaneous application with antitussive agents - opioid receptor agonists and other drugs, depressant drug, shows synergy. When combined with the use of MAO inhibitors can not exclude the possibility of interaction (this combination is contraindicated).

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The drug is approved for use as a non-prescription medicines.

Terms and Conditions of storage

The drug should be stored in a dry, protected from light and away from children at or above 25 ° C. Shelf life - 2 years.