2010/06/05

Heparin sodium+Benzocaine+Benzonicotinic acid

International name:
Heparin sodium + benzocaine + Benzonikotinovaya acid (Heparin sodium + Benzocaine + Benzonicotinic acid)

Group Affiliation:
Anticoagulant line for local use

Description of the active substance (INN):
Heparin sodium + benzocaine + Benzonikotinovaya acid

Dosage form:
ointment for external use

Mode of action:
Combined preparation for external use, the effect is caused by properties of its constituent components. Anticoagulant of direct action. Eventually release of heparin sodium ointment reduces inflammation and has antithrombotic effects. Promotes the resorption of existing and prevents the formation of new clots. It blocks the synthesis of thrombin, reducing platelet aggregation. Inhibits the activity of hyaluronidase, activates the fibrinolytic properties of blood. Benzyl ester of nicotinic acid increases the surface blood vessels, promoting absorption of heparin. The local anesthetic benzocaine reduces the severity of pain. When applied to the skin has a local analgesic effect.

Indications:
Thrombophlebitis of superficial veins (prevention and treatment), and postinektsionny postinfuzionny phlebitis, external hemorrhoids, inflammation, postnatal hemorrhoids, sores leg, elephantiasis, surface periflebit, lymphangitis, mastitis superficial, localized infiltrates and edema, trauma and injuries (including muscle tissue, tendons, joints), subcutaneous hematoma.

Contraindications:
Hypersensitivity, ulcerous-necrotic processes, violating the integrity of skin pokrovov.C caution. Thrombocytopenia, increased bleeding.

Side effects:
Skin hyperemia, allergic reactions.

Dosage and administration:
Outwardly. The ointment is applied a thin layer to affected area (estimated at 0.5-1 g per plot with a diameter of 3-5 cm) and gently rubbed into the skin 2-3 times a day every day until the disappearance of inflammation, on average, from 3 to 7 days. The possibility of a longer course of treatment is determined by your doctor. Thrombosis of external hemorrhoids, rectal swabs are used, ointment is applied to calico or linen strip, which is imposed directly on the thrombosed parts and fix. The ointment should be applied daily until symptoms disappear, an average of 3-14 days. With the same purpose, you can use a swab soaked with grease, which is introduced into the anus.

Cautions:
Should not be applied to open wounds, in the presence of purulent processes. Application of the ointment is not recommended for deep venous thrombosis.

Interaction:
Do not appoint local concurrently with NSAIDs, tetracycline antibiotics, antihistamine drugs.