2010/06/05

DEANOL ACEGLUMATE

Pharmacological action

Nootropic drug, on chemical structure similar to natural metabolites of the brain (GABA, glutamic acid). Has tserebroprotektornoe action, restores mental alertness, improves learning, easier processes for capturing, consolidating and play a memorable track. Stimulates tissue metabolism, increases the amplitude of transkallozalnogo capacity, improves the organization of the basic rhythm of EEG and smooths the interhemispheric asymmetry. Has a positive effect in neurotic states in elderly and senile, developed against the background of organic insufficiency of the brain in alcohol-withdrawal syndrome.


Pharmacokinetics

C max in the CNS after oral administration is achieved by 0.5-1 h, to a lesser extent penetrate into the liver, lungs, heart, kidneys. T 1 / 2 to 24 h, displayed by the kidneys.


Statement

Astenodepressivnye state (border states psychoorganic syndrome, schizophrenia, alcoholism), Neuroleptic malignant syndrome (correction of mild and severe forms), abstinence alcohol syndrome (with a predominance of asthenic disorders and somatovegetativnyh), intellectual mnesticheskih violations, psychosomatic illness, during convalescence after suffered traumatic -cerebral trauma, cerebrovascular disease (especially in elderly and senile).


Dosage regimen

Inward 1 g 2-3 times / day, the last admission - no later than 16-18 hours on average daily intake for adults - 4-6 g, for children - 0.5-2, the treatment duration - 1.5-2.5 months, 2 - 3 times a year.

Maximum dose: single - 2 grams daily - 1910


Side effect

Perhaps: allergic reactions, headaches, sleep disturbance, constipation, weight loss, itching.

In some cases: depression (elderly patients).


Contraindications

Hypersensitivity, infectious diseases, central nervous system, feverish condition, blood diseases, psychotic conditions, renal and / or hepatic impairment, epilepsy, pregnancy, lactation.


Application of pregnancy and breastfeeding

Deanol atseglumat contraindicated during pregnancy and lactation (breastfeeding).


Cautions

Effects on ability to drive vehicles and management mechanisms

During the period of treatment should refrain from driving motor vehicles and classes of potentially hazardous activities that require high concentration and speed of psychomotor reactions.


Drug Interactions

Perhaps strengthening the action of drugs stimulating the central nervous system.