2010/12/17

Bezpa

Release forms - tablets (Valium) 40 mg Bezpa 

Pharmacotherapeutic group - antispasmodic

Pharmacological action
vasodilating
spasmolytic

Ingredients - drotaverine 40 mg, excipients (lactose, sodium metabilsulfit, povidone K 25, croscarmellose sodium, magnesium stearate, isopropyl alcohol, water)

Statement
Gastrojejunal ulcer
Arteritis unspecified
Pain in the abdomen and pelvis
Headache
Pain, unspecified
Pain, not elsewhere classified
Pain associated with urination
Pain and other conditions associated with female sexual organs and the menstrual cycle
Diseases of the gallbladder, biliary tract and pancreas
Painful urination, unspecified
Secondary dysmenorrhea
Constipation
Stones of the bile duct with cholecystitis
Common symptoms and signs
Miscarriage
Pilorospazme, not elsewhere classified
Unspecified renal colic
Acute cholecystitis
Noninfectious gastroenteritis and colitis, unspecified
Noninfectious enteritis and colitis
Peptic ulcer unspecified location
Spontaneous abortion
Symptoms and signs involving the urinary system
Symptoms and signs involving the digestive system and abdomen
Somatoform dysfunction of the autonomic nervous system
Somatoform disorders
Vascular headache, not elsewhere classified
Vascular diseases of intestines
Vascular disease intestine unspecified
Chronic cholecystitis
Chronic vascular disease
Cholecystitis
Cholecystitis, unspecified
Tenesmus of the bladder
Other diseases of anus and rectum
Other diseases of intestines
Other diseases of esophagus
Other diseases of stomach and duodenum
Other diseases of gallbladder
Other and unspecified abdominal pain
Other disorders of arteries and arterioles
Other noninfectious gastroenteritis and colitis
Other symptoms and signs involving the digestive system and abdomen
Other headache syndromes
Other forms of cholecystitis
Other functional intestinal disorders
Other specified diseases of the anus and rectum
Other specified diseases of gallbladder
Other specified non-infectious gastroenteritis and colitis
Dysuria
Dysmenorrhea, unspecified
Cholelithiasis
Ulcer of the esophagus
Duodenal ulcer
Gastric ulcer

The composition of the components
water
lactose
croscarmellose sodium
magnesium stearate
sodium metabisulfite
povidone
propyl alcohol
drotaverine

Pharmacodynamics

Myotropic antispasmodic. Lowers the tone of smooth muscles of internal organs, reducing their locomotor activity, dilates blood vessels. No effect on the autonomic nervous system, does not penetrate the CNS. In connection with the direct influence on smooth muscle, can be used as a spasmolytic in cases where the drugs are contraindicated in the group holinoblokatorov (glaucoma, prostatic hypertrophy). With / in the introduction beginning effect - after 2-4 minutes, with maximal effect develops after 30 minutes.

Pharmacokinetics

With oral absorption - high, period poluabsorbtsii - 12 min. Bioavailability - 100%.

Application

Prevention and treatment of functional states, and pain caused by spasm of smooth muscle: renal colic, pyelitis, spasm of the ureter, biliary colic, biliary dyskinesia gipermotornaya and gall bladder, cholecystitis, intestinal colic, spastic constipation, spastic colitis, proctitis, tenesmus, pilorospazme. Peptic ulcer and 12 duodenal ulcer in acute phase (in the complex therapy). Pain syndrome spasm of peripheral arteries (endarteritis), brain vessels, coronary arteries. Algomenorrhea, the threat of miscarriage and premature birth, spasm of the cervix during labor, prolonged opening the throat, afterpains. To conduct some instrumental studies, cholecystography.

Dosing regimen

Adults inside appoint 40-80 mg 3 times / day / m, n / k - by 40-80 mg 1-3 times / day. For relief of hepatic and renal colic is administered IV slowly 40-80 mg. When peripheral vascular spasm medication can be administered intraarterially. Children under the age of 6 years, to appoint a single dose of 10-20 mg, 6-12 years - 20 mg, the multiplicity of destination 1-2 times / day.

Side Effects

Dizziness, palpitations, hot flashes, sweating. With / in the introduction hypotension, collapse, AV block, arrhythmias, depression of the respiratory center.

Contraindications

Hypersensitivity, glaucoma, prostate adenoma. With care - patients with severe coronary atherosclerosis, and pregnancy.

Interaction

Reduces antiparkinsonian effect of levodopa.

Cautions

In the treatment of gastric ulcer and 12 duodenal ulcer is used in combination with other antiulcer agents.

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