Berocca Plus

Release form, composition and packing Berocca Plus 

Effervescent Tablets Valium, from pale orange to pale orange, with patches of darker and lighter in color, soluble in water, emitting bubbles forming a solution with the smell of oranges.

1 tab.

ascorbic acid (vit. C) 500 mg.

Thiamin (B1 vit.) 15 mg.

riboflavin (vit. B2) 15 mg.

pantothenic acid (B5 vit.) 23 mg.

pyridoxine hydrochloride (vit. B6) 10 mg.

Folic Acid (vit. Bc) 400 mcg.

cyanocobalamin (vit. B12) 10 mcg.

nicotinamide (vit. PP) 50 mg.

biotin (vit. H) 150 mcg.

Calcium 100 mg.

Magnesium 100 mg.

Zinc 10 mg.

Inactive ingredients: citric acid anhydrous, sodium bicarbonate, sodium carbonate anhydrous, sodium chloride, acesulfame potassium, aspartame, mannitol, polysorbate 60, betakaroten (E160a), beet red dye (E162), orange flavor.

Clinico-pharmacological group: Multivitamins with macro-and micronutrients.

Pharmacological action

Combination drug pharmacological effect which is due to its constituent complex of vitamins and minerals. B vitamins are involved in many metabolic reactions, including synthesis of neurotransmitters.

Vitamin C (ascorbic acid) is a biological antioxidant and plays an important role in the inactivation of free radicals, increases iron absorption in the intestine, affects the metabolism of folic acid and the function of leukocytes.

Stimulates the formation of connective tissue, bone, and normalizes capillary permeability.

Calcium is involved in many physiological processes, enzyme systems and transmission of nerve impulses in combination with magnesium and vitamin B6.

Magnesium is involved in various reactions, including protein synthesis, fatty acid metabolism, oxidation of sugars.

Zinc as a catalyst activates over 200 enzymes and is a component of many proteins, neuropeptides, hormone receptors, and also directly involved in the synthesis of coenzyme derivatives of vitamin B6. Vitamin content in the product Berezhko * Plus chosen for use in therapy and is used for conditions involving deficiency or an increased need for vitamins (increased exercise, a period of prolonged nervous strain, and stress, with defective and unbalanced diet (restricting diet) in the elderly people, chronic alcoholism, nicotine dependence (smokers), as well as use of oral contraceptives in women).

Water-soluble vitamins do not accumulate in the body, so when you state, accompanied by increased demand for vitamins and minerals, vitamins, arriving with food, may be inadequate.

Deficit or condition associated with an increased need for B vitamins, vitamin C and zinc.

Dosing regimen

The drug is taken orally, after dissolving the tablet in a glass of water.

Adults and children 15 years: 1 tablet per day.

Do not exceed recommended daily dose of the drug.

The recommended duration of treatment is 30 days. Repeated courses on the recommendation of a physician.

Side effect

Allergic reaction: In very rare cases (<1 / 10,000) may be hives, rashes, swelling of the throat.

Digestive system: less than 5% of patients may be slight transient gastrointestinal disturbances.

Blood and hematopoietic system: patients with deficiency of glucose-6-phosphate dehydrogenase deficiency ascorbic acid may cause hemolytic anemia.

hypersensitivity to the drug, hypercalcemia, gipermagniemiya, urolithiasis (nephrolithiasis, urolithiasis), hemochromatosis, hyperoxaluria, renal failure, deficiency of glucose-6-phosphate dehydrogenase, children under the age of 15 years.

With caution in atrophic gastritis, intestinal diseases, pancreatic insufficiency syndrome intake of vitamin B12 or congenital deficiency of intrinsic factor Castle.

Pregnancy and lactation

Using the drug Berokka Plus at the recommended dosage of data about the negative effects of the drug on pregnancy or the child's health is not revealed. However, during pregnancy, the drug should be taken strictly on medical grounds.

Vitamins and minerals contained in the drug Berokka Plus, get into breast milk. Data on the safety of the drug when applied during lactation no.


Vitamin C may affect the test results to determine glucose in urine, despite the fact that it does not affect blood sugar levels. Vitamin C should be terminated within a few days before carrying out such tests.

Possible staining of urine into the yellow color that has no clinical significance and attributed to the presence in the preparation of riboflavin.

Product does not contain fat-soluble vitamins. One tablet of the drug contained a maximum daily dose of vitamin B6 (pyridoxine), and therefore should not exceed the recommended dose of medication.

One tablet contains 12,5% of the recommended daily intake of calcium and 33.3% of the recommended daily intake of magnesium. However, for the treatment of deficiency of calcium and magnesium receiving only drug Berokka * Plus is insufficient.

B Each tablet contains 272 mg of sodium, so patients that keep low-salt diet is recommended to take the drug Berokka "Plus, in the form of coated tablets.

Information for patients with diabetes diabetom.V one tablet preparation contains 276 mg of mannitol, which corresponds to 0.028 unit of grain (XE), and energy value of 0.66 kcal, and the drug can be administered to patients with diabetes mellitus. Patients taking other medications should consult with your doctor before you start taking the drug Berokka * Plus.

Effect on ability to drive a car or moving machinery. Not affected.


Cases of overdose were reported.

Symptoms of overdose may include gastrointestinal disturbances such as diarrhea and discomfort in the stomach. Excessive intake of vitamin B6 (over 20 pills a day and within a few months) can lead to symptoms of neuropathy.

In case of overdose, discontinue the drug and consult a doctor.

Drug Interactions

Vitamin World Bank (pyridoxine) at a dose exceeding 5 mg, may neutralize the effect of levodopa in patients with Parkinson's disease. However, this antagonism does not occur if levodopa is used in combination with a decarboxylase inhibitor (eg, benserazide, arbidopa).

Thiosemicarbazone and 5-flyuorouratsil neutralize the action of vitamin B1.

Antacids inhibit the resorption of vitamin B1.

Neomycin, aminosalicylic acid, and H2-6lokatory reduce the absorption of vitamin B12.

Aspirin reduces the absorption of ascorbic acid by about a third.

Oral contraceptives can reduce the level of serum vitamin B12, folic acid, pyridoxine, ascorbic acid. Some patients take daily deferoxamine and vitamin C 500 mg, may experience transient left ventricular dysfunction.

Conditions and terms of

Keep out of reach of children. At a temperature not exceeding 25 ° C in tightly closed containers.

Shelf life - 2 years.