2010/12/17

Betadine

Release form, composition and packing Betadine 

Solution for local and topical application of 10% dark brown color that does not contain suspended or precipitated particles. 1 mL of povidone-iodine 100 mg. Other ingredients: glycerol, nonoxynol 9, citric acid (anhydrous), disodium hydrogen phosphate, sodium hydroxide, p-p 10% (to maintain the pH), purified water.

Clinico-pharmacological group: Antiseptic for external and local application.

Pharmacological action

Antiseptic drug. Extracted from the complex with polyvinylpyrrolidone in contact with skin and mucous membranes, iodine forms a protein bacterial cells yodaminy, coagulates it and causes the death of microorganisms. Provides rapid bactericidal action on gram-positive and gram-negative bacteria (excluding M. tuberculosis). Effective against fungi, viruses, protozoa.

Pharmacokinetics

Suction

When applied topically are absorbed almost no iodine.

Statement
treatment and prevention of wound infections in surgery, traumatology, Combustiology, dentistry;
treatment of bacterial, fungal and viral skin infections, prevention of superinfection in dermatological practice;
treatment of pressure sores, venous ulcers, diabetic foot;
Disinfection of the skin and mucous membranes of patients in preparation for surgery, invasive studies (including punctures, biopsies, injection);
Disinfection of the skin around the drains, catheters, probes;
disinfection of oral cavity in dental operations;
Disinfection of the birth canal, during the "small" gynecological surgery (including abortion, IUD insertion, coagulation and the erosion of the polyp).

Dosing regimen

For the treatment of skin and mucous Betadine solution is used undiluted for lubricating, washing or as a wet compress. For use in drainage systems, 10% solution was diluted from 10 to 100 times. The solution was prepared immediately before use, dilute solutions do not store.

Side effect

Allergic reactions: hypersensitivity reactions to the drug, requiring drug withdrawal manifestations of allergic reactions - redness, burning, itching, swelling, and pain.

Contraindications
dysfunction of the thyroid gland (hyperthyroidism);
thyroid adenoma;
Dermatitis herpetiformis Duhring;
simultaneous use of radioactive iodine;
premature and newborn babies;
Hypersensitivity to iodine and other ingredients.

With careful use of medication in chronic renal failure.

Pregnancy and lactation

Application of Betadine is not recommended to the third month of pregnancy and lactation (breastfeeding). If necessary, in these cases, treatment is possible for individual medical supervision.

Use in renal impairment

Caution must be exercised with regular use on damaged skin in patients with chronic renal failure.

Cautions

If you frequently use a large area of the wound surface and mucous membranes may occur systemic reabsorption of iodine, which can affect the tests of functional activity of the thyroid gland.

In violation of thyroid function to use the drug only under strict medical supervision. Use of the drug in newborn infants is possible only if necessary, after the study of thyroid function.

Caution must be exercised with regular use on damaged skin in patients with chronic renal failure. Care should be taken to a patient may not remain over the solution. Do not heat the solution before use.

In place of colored film is formed, continuing to release the total number of active iodine, which means the cessation of the drug. Coloration of the skin and tissues is easily washed off with water. Do not use insect stings, domestic and wild animals.

Overdose

Data on drug overdose Betadine is not available.

Drug Interactions

Betadine is incompatible with other antiseptics, particularly those containing alkali, enzymes and mercury. In the presence of blood bactericidal activity may decrease, but with increasing concentration, bactericidal activity can be increased.

Conditions and terms of

List B. The drug should be kept away from children, dry, dark place at temperatures from 5 ° to 15 ° C. Shelf life - 3 years.