2010/12/17

Betagenot

Release form, composition and packing Betagenot 

Drops eye / ear in the form of transparent, colorless or slightly yellowish liquid. 1 mL betamethasone sodium phosphate (in terms of dry matter) 1.316 mg of gentamicin (in the form of sulphate) 3 mg. Excipients: sodium phosphate, monosodium, sodium phosphate dibasic, sodium tetraborate, sodium citrate, sodium chloride, Disodium EDTA (Trilon B), benzalkonium chloride, water, d / and.

Clinico-pharmacological group: drug with anti-bacterial and anti-inflammatory action for topical use in ophthalmology and ENT practice.

Pharmacological action

Combined medication with anti-bacterial and anti-inflammatory, containing betamethasone and gentamicin.

Gentamicin - a broad spectrum antibiotic aminoglycoside, bactericidal effect. Active against Staphylococcus aureus (coagulase-positive and coagulase-negative strains, as well as some strains of penicillinase producing), Pseudomonas aeruginosa, Proteus spp. (Indole-positive and indole-negative strains), Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, Haemophilus aegypticus, Aerobacter atrogenes, Moraxella lacunata (wand-Morakca Aksenfelda), Neisseria spp. (Including Neisseria gonorrhoeae). Betamethasone - GCS provides local anti-inflammatory, vasoconstrictive and anti-allergic effect. Inhibits fibroblastic processes and the formation of collagen slows down the process of regeneration of the epithelium, inhibits the process of neovascularization in the inflammation, reduces the permeability of the vascular wall.

Statement

Eye diseases:
Allergy and Infectious Diseases of the anterior eye, caused by pathogens sensitive to gentamicin (including conjunctivitis, keratitis, blepharitis, barley);
Prevention and treatment of inflammatory complications in the postoperative period (removal of cataract surgery for glaucoma).

Diseases of the ear:
Allergic otitis externa;
infective otitis media caused by pathogens sensitive to gentamicin (except otitis viral etiology);
chronic eczematous otitis externa;
seborrheic otitis externa;
chronic skin disease ear canal, including Lichen simplex chronicus.

Dosing regimen

In eye diseases drug instill 1-2 drops into the lower conjunctival sac 4-6 times / day.

In diseases of the ear medication is instilled with 3-4 drops into the ear canal every 2-3 hours after achieving clinical improvement should gradually reduce the multiplicity of the drug to the required, provide control over symptoms.

Side effect

On the part of the vision: the extremely rare - the thinning or perforation of the cornea, sclera, increased intraocular pressure, posterior subcapsular cataract formation, secondary infection, the spread of Herpes simplex, a burning sensation, the narrowing field of vision, acute anterior uveitis, mydriasis, accommodation paresis, ptosis, allergic reactions.
From the hearing organ: a burning sensation, pain and tingling in the ear, dermatitis, ear canal. Systemic reactions: suppression of adrenal function.

Contraindications
fungal eye;
Acute viral infections of the eye (including acute superficial keratitis caused by Herpes simplex);
tuberculous eye disease;
thinning, or a defect of the epithelium of the cornea, sclera;
glaucoma;
trachoma;
fungal skin meatus;
tuberculous lesions ear;
Acute viral infections of the ear;
chronic otitis media or acute otitis media in history;
violating the integrity of the tympanic membrane (possibly the development of ototoxicity);
Infancy;
Hypersensitivity to betamethasone, gentamicin or other ingredients.

Caution should be used drug in heart failure, hypertension, marked renal impairment and liver, nephrolithiasis, diabetes mellitus, high myopia, open-angle glaucoma.

Pregnancy and lactation

The drug is not recommended during pregnancy and lactation.

Cautions

The drug Betagenot should control the intraocular pressure, lens status, since the possible development of steroid glaucoma and cataracts. If you use contact lenses they must be removed before instillation of the drug and re-establish within 15 minutes after the procedure.

Effects on ability to drive vehicles and management mechanisms

Use caution when working with machinery and driving.

Overdose

No cases of overdose Betagenot were reported.

Drug Interactions

Drug interactions drug Betagenot with other drugs has not been described.

Conditions and terms of

List B. The drug should be kept in the dark, place inaccessible to children, at temperatures from 0 ° to 25 ° C. Shelf life - 2 years