2010/12/12

Ascoril Expectorant

Release form, composition and packing

Syrup 10 ml of salbutamol (in the form of sulfate) 2 mg Bromhexine hydrochloride 4 mg gvayfenezin 100 mg Menthol 1 mg. Other ingredients: flavors, sucrose, sodium benzoate, sorbitol, glycerol, propylene glycol, dye Sunset Yellow, purified water.

Clinico-pharmacological group: preparation with mucolytic, expectorant and bronchodilator effect.

Pharmacological action

Combined medication with a bronchodilator and expectorant. Salbutamol - a selective β2-adrenoceptor agonist, has a bronchodilator effect, relieves bronchospasm.

Bromhexine has mucolytic action. Reduces the viscosity of bronchial secretions due to depolarization of acidic polysaccharides and stimulation of secretory cells of mucous membranes of the bronchi.

Gvayfenezin reduces surface tension and adhesion properties of sputum, promotes its expectoration.

Menthol has antispasmodic effect, gently stimulates the secretion of bronchial glands, has antiseptic properties and restores the function of ciliated epithelium of bronchial mucosa.

Pharmacokinetics

Data on the pharmacokinetics of the drug Ascoril Expectorant is not available.

Statement
bronchial asthma;
Acute and chronic bronchitis;
bronchiectasis;
atelectasis;
emphysema;
pneumonia;
pertussis;
pulmonary tuberculosis;
bronhospasticheskih other states.

Dosing regimen

Adults appoint 10 ml (2 teaspoons) 3 times a day.

Children under 6 years - 5 ml (1 teaspoon) 3 times per day, from 6 to 12 years - to 5-10 ml (1-2 teaspoons) 3 times a day. If necessary, dosage may be increased.

Side effect

Rare: hand tremor, tachycardia, muscle cramps. When used in high doses - tachycardia, headache, peripheral vasodilatation.

Contraindications
tachycardia;
Cardiac arrhythmia;
hypersensitivity to the drug.

Pregnancy and lactation

Adequate and well-controlled clinical studies on the safety of the drug Ascoril Expectorant during pregnancy and lactation (breastfeeding) was conducted. In connection with this application of the drug is only possible in cases where the potential benefits to the mother justifies the perceived risk to the fetus or child.

Cautions

With carefully administered to patients with hyperthyroidism, diabetes, severe diseases of the cardiovascular system, hypertension, gastric ulcer and duodenal ulcer. Should not be used Ascoril Expectorant, in combination with beta-blockers.

Overdose

Symptoms: may increase manifestations described side effects.

Treatment: If necessary, symptomatic treatment.

Drug Interactions

With the simultaneous application of sympathomimetics and theophylline increase the effect and increase the likelihood of side effects of salbutamol, which is part of the preparation Ascoril Expectorant.

Conditions and terms of

The drug should be kept in the dark at a temperature not exceeding 25 ° C. Shelf life - 2 years.