Release form, composition and packing
Cream for external use only 0.05% of a homogeneous, white.
1 g alclometasone dipropionate 500 mcg.
Other ingredients: propylene glycol, hlorkrezol, sodium phosphate monoosnovnoy dihydrate, phosphoric acid, cetostearyl alcohol, macrogol cetostearyl ether 22, glyceryl stearate, PEG-100 stearate, petrolatum white, sodium hydroxide, purified water.
Ointment for external use only 0.05% of a homogeneous, white or pale yellow.
1 g alclometasone dipropionate 500 mcg.
Other ingredients: hexylene glycol, propylene glycol monostearate, white petrolatum, white wax.
Clinico-pharmacological group: SCS for outdoor use.
Pharmacological action
Fluorinated synthetic corticosteroids for topical use. Has anti-inflammatory, antiallergic, antipruritic and anti-proliferative effect.
When applied to the skin surface in the inflammation quickly and effectively reduces the severity of objective symptoms (erythema, edema, lihenifikatsiya) and subjective sensations (itching, irritation, pain).
Pharmacokinetics
Data on the pharmacokinetics of the drug Afloderm not given.
Statement
Dermatoses, in which effective topical therapy of GCS (including the localization on the face and anogenital region):
atopic dermatitis;
eczema;
psoriasis;
allergic and contact dermatitis;
solar dermatitis;
Allergic reactions to insect stings.
The drug can be administered to children from 6 months.
Dosing regimen
The cream is recommended for the treatment of acute, including weeping skin lesions, the ointment - for the treatment of subacute and chronic dermatoses, including dry, scaly lesions and lihenizirovannyh, or in cases where it is necessary occlusal force ointment. Cream or ointment is applied uniformly thin layer to affected skin 2-3 times daily. At sites with more dense skin (eg elbows, hands and feet) as well as places from which the drug is easily erased, Afloderm should be applied more frequently. The children in the period stihaniya main symptoms drug can be used 1 time per day.
For relapse prevention in the treatment of chronic therapy should continue for some time after the disappearance of all symptoms.
Side effect
Side effects when applied externally alclometasone occur rarely and are reversible. Dermatological reactions: 1-2% of patients may develop itching, burning, redness or dryness, irritation, papular rash, very rarely - aknepodobnye changes, hypopigmentation, miliaria, folliculitis, striae, skin atrophy, hypertrichosis, allergic contact dermatitis, secondary infection skin.
Contraindications
lupus;
cutaneous manifestations of syphilis;
chickenpox;
Viral infections of the skin;
skin reactions post-vaccination;
open wounds;
trophic ulcers;
rosacea;
acne vulgaris;
Hypersensitivity to alclometasone or any of the supporting components of the drug.
Pregnancy and lactation
Application Afloderma during pregnancy is only possible if the intended benefits to the mother outweighs the potential risk to the fetus. In such cases, the use of the drug should be brief and confined to a small area of skin. Data on the teratogenic effect of the drug available. Possible use of the drug Afloderm during lactation, but with caution, in particular, the drug should not be applied to the skin of the breast before feeding.
Cautions
If the first application Afloderma develop hypersensitivity reactions (itching, burning and redness), the drug should be discontinued. Afloderm should not be applied to the skin around the eyes (due to the possible development of glaucoma and cataracts), as well as on the open wound.
If the disease is complicated by the development of secondary bacterial or fungal infection, to therapy with Afloderm need to add specific antibacterial or antifungal agent.
Use in pediatrics
The drug can be used in young children. Keep in mind that young children skin folds and diaper may have an effect similar to the effect of occlusive dressings, and increase, respectively, the systemic absorption of the active substance.
In addition, in children the greatest possible degree of systemic absorption because of the relation between the surface of the skin and body mass, as well as the insufficient maturity of the epidermis. Therefore, long-term use in young children is possible only under medical supervision.
Overdose
Data on drug overdose Afloderm not given.
Drug Interactions
Not established clinically significant drug interactions Afloderm with other drugs.
Conditions and terms of
The drug should be stored in a place inaccessible to children at or above 30 ° C. Shelf life Cream - 2 years, ointments - 3 years.
Cream for external use only 0.05% of a homogeneous, white.
1 g alclometasone dipropionate 500 mcg.
Other ingredients: propylene glycol, hlorkrezol, sodium phosphate monoosnovnoy dihydrate, phosphoric acid, cetostearyl alcohol, macrogol cetostearyl ether 22, glyceryl stearate, PEG-100 stearate, petrolatum white, sodium hydroxide, purified water.
Ointment for external use only 0.05% of a homogeneous, white or pale yellow.
1 g alclometasone dipropionate 500 mcg.
Other ingredients: hexylene glycol, propylene glycol monostearate, white petrolatum, white wax.
Clinico-pharmacological group: SCS for outdoor use.
Pharmacological action
Fluorinated synthetic corticosteroids for topical use. Has anti-inflammatory, antiallergic, antipruritic and anti-proliferative effect.
When applied to the skin surface in the inflammation quickly and effectively reduces the severity of objective symptoms (erythema, edema, lihenifikatsiya) and subjective sensations (itching, irritation, pain).
Pharmacokinetics
Data on the pharmacokinetics of the drug Afloderm not given.
Statement
Dermatoses, in which effective topical therapy of GCS (including the localization on the face and anogenital region):
atopic dermatitis;
eczema;
psoriasis;
allergic and contact dermatitis;
solar dermatitis;
Allergic reactions to insect stings.
The drug can be administered to children from 6 months.
Dosing regimen
The cream is recommended for the treatment of acute, including weeping skin lesions, the ointment - for the treatment of subacute and chronic dermatoses, including dry, scaly lesions and lihenizirovannyh, or in cases where it is necessary occlusal force ointment. Cream or ointment is applied uniformly thin layer to affected skin 2-3 times daily. At sites with more dense skin (eg elbows, hands and feet) as well as places from which the drug is easily erased, Afloderm should be applied more frequently. The children in the period stihaniya main symptoms drug can be used 1 time per day.
For relapse prevention in the treatment of chronic therapy should continue for some time after the disappearance of all symptoms.
Side effect
Side effects when applied externally alclometasone occur rarely and are reversible. Dermatological reactions: 1-2% of patients may develop itching, burning, redness or dryness, irritation, papular rash, very rarely - aknepodobnye changes, hypopigmentation, miliaria, folliculitis, striae, skin atrophy, hypertrichosis, allergic contact dermatitis, secondary infection skin.
Contraindications
lupus;
cutaneous manifestations of syphilis;
chickenpox;
Viral infections of the skin;
skin reactions post-vaccination;
open wounds;
trophic ulcers;
rosacea;
acne vulgaris;
Hypersensitivity to alclometasone or any of the supporting components of the drug.
Pregnancy and lactation
Application Afloderma during pregnancy is only possible if the intended benefits to the mother outweighs the potential risk to the fetus. In such cases, the use of the drug should be brief and confined to a small area of skin. Data on the teratogenic effect of the drug available. Possible use of the drug Afloderm during lactation, but with caution, in particular, the drug should not be applied to the skin of the breast before feeding.
Cautions
If the first application Afloderma develop hypersensitivity reactions (itching, burning and redness), the drug should be discontinued. Afloderm should not be applied to the skin around the eyes (due to the possible development of glaucoma and cataracts), as well as on the open wound.
If the disease is complicated by the development of secondary bacterial or fungal infection, to therapy with Afloderm need to add specific antibacterial or antifungal agent.
Use in pediatrics
The drug can be used in young children. Keep in mind that young children skin folds and diaper may have an effect similar to the effect of occlusive dressings, and increase, respectively, the systemic absorption of the active substance.
In addition, in children the greatest possible degree of systemic absorption because of the relation between the surface of the skin and body mass, as well as the insufficient maturity of the epidermis. Therefore, long-term use in young children is possible only under medical supervision.
Overdose
Data on drug overdose Afloderm not given.
Drug Interactions
Not established clinically significant drug interactions Afloderm with other drugs.
Conditions and terms of
The drug should be stored in a place inaccessible to children at or above 30 ° C. Shelf life Cream - 2 years, ointments - 3 years.
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