Release form, composition and packing Beplex 
Solution for injection 1 ml 1 amp. thiamin (as hydrochloride) 5 mg 10 mg Riboflavin 2 mg, 4 mg pyridoxine (as hydrochloride) 2 mg, 4 mg cyanocobalamin 4 micrograms 8 mg dexpanthenol 3 mg 6 mg Nicotinamide 20 mg 40 mg. Inactive ingredients: polysorbate 80, benzyl alcohol, water, d / and.

Clinico-pharmacological group: Multivitamins.

Pharmacological action

Multivitamin preparations containing vitamins B, the pharmacological effect is due to the properties of its constituent vitamins. Thiamin (vitamin B1) as a coenzyme involved in the metabolism of carbohydrates, amino acids, the synthesis of RNA / DNA, bile acids, neurotransmitters. Riboflavin (vitamin B2) - an important catalyst of cellular respiration and visual perception.

Provides most of the redox reactions involved in metabolism of carbohydrates, fats and amino acids.

Pyridoxine (vitamin B6) as a coenzyme involved in the metabolism of amino acids and proteins in the synthesis of neurotransmitters.

Cyanocobalamin (Vitamin B12), together with folic acid is involved in the synthesis of nucleotides, involved in the formation of red blood cells and nerve cell membranes necessary for the growth of the organism.

Nicotinamide (vitamin PP, vitamin B3) is involved in tissue respiration, metabolism of fats, carbohydrates, amino acids.

Dexpanthenol (Vitamin B5) as an integral part of coenzyme A plays an important role in the processes of acetylation and oxidation of carbohydrates and fats, synthesis of bile acids, the synthesis of hormones.


Data on the pharmacokinetics of the drug Bepleks not given.

unbalanced diet;
malabsorption of vitamins in the intestine (sprue, diarrhea, and prolonged antibiotic therapy);
Prevention and treatment of neurological diseases (including neuritis, radiculitis, neuralgia, peripheral paralysis, diabetic polyneuropathy);
neurological disorders caused by chronic alcoholism;
diseases of the oral mucosa (glossitis, gingivitis, stomatitis);
digestive diseases (gastritis, gastric ulcer and duodenal ulcer, chronic colitis);
liver disease (including chronic hepatitis);
skin diseases (long-term non-healing wounds, burns, cracks in the corners of the mouth);
ophthalmic diseases (conjunctivitis, iritis, corneal ulcer, cataract);
metabolic disorders;
Lactation (breastfeeding).

Dosing regimen

The drug is prescribed in a / m / in adults and children over 12 years of 2-4 ml / day.

Side effect

Possible: an allergic reaction.

increased sensitivity to the B vitamins;
concurrent levodopa therapy.

Pregnancy and lactation

In applying Bepleksa at recommended doses were observed any negative effects on the fetus. In high doses, pyridoxine violates the release of prolactin, so the drug should be used with caution during lactation.


Keep in mind that when receiving Bepleksa possible staining of the urine in yellow color, that due to the presence of the drug riboflavin. Efficacy of the drug in excessive doses for different diseases is not justified.


Symptoms: nausea, vomiting, pale skin.

Treatment: symptomatic therapy.

Drug Interactions

Pyridoxine, which is part of the preparation Bepleks may increase the metabolism of levodopa, reducing the therapeutic activity of this drug. Joint application Bepleksa and levodopa is possible only with concomitant administration of inhibitors of decarboxylase.

Pyridoxine may decrease the effects of steroid hormones. Isoniazid increases the excretion of pyridoxine in the urine. Cycloserine, hydralazine, and penicillamine are antagonists of thiamine, which is part of the preparation Bepleks. Not recommended simultaneous use of the drug Bepleks with derivatives of HMG-CoA reductase inhibitors (lovastatin, pravastatin), because the interaction of these drugs is possible rhabdomyolysis.

Conditions and terms of

The drug should be stored out of reach of children, protected from light at temperature above 25 ° C. Do not freeze. Shelf life - 3 years.