2010/12/16

Belogent

Release form, composition and packing Belogent 

Cream for external use only white, homogeneous, without mechanical impurities. 1 g of betamethasone dipropionate 640 mcg, which resp. content of betamethasone 500 mcg gentamicin (in the form of sulfate) 1 mg. Excipients: hlorokrezol, sodium dihydrogen phosphate monohydrate, phosphoric acid, petroleum jelly white mineral oil, macrogol cetostearyl ether 22, cetostearyl alcohol, sodium hydroxide, purified water.

Ointment for external use only white, translucent, homogeneous. 1 g of betamethasone dipropionate 640 mcg, which resp. content of betamethasone 500 mcg gentamicin (in the form of sulfate) 1 mg. Other ingredients: mineral oil, petroleum jelly white.

Clinico-pharmacological group: drug with anti-bacterial and anti-inflammatory effect for outdoor use.

Pharmacological action

Drug with anti-bacterial, anti-inflammatory and antiallergic effect for outdoor use. Betamethasone has anti-inflammatory, antiallergic, antipruritic and anti-proliferative effect.

When applied to the skin surface, betamethasone has a rapid and dramatic effect in the inflammation, reducing the severity of objective symptoms (erythema, edema, lihenifikatsiya) and subjective sensations (itching, irritation, pain). Gentamicin has a broad spectrum bactericidal activity against most gram-positive and Gram-negative microorganisms, including strains of Streptococcus spp. (Beta-hemolytic, alpha-hemolytic), Staphylococcus aureus (coagulase positive, coagulase-negative and some strains of penicillinase producing), Proteus spp., Escherichia coli.

Pharmacokinetics

Data on the pharmacokinetics of the drug Belogent not given.

Statement

Dermatitis, allergic and inflammatory skin diseases for which effective treatment with topical corticosteroids, and within which is complicated by bacterial infection or a risk of its accession, including:
eczema;
atopic dermatitis;
diffuse neurodermatitis;
contact (including professional) dermatitis;
atopic dermatitis;
seborrheic dermatitis;
impetigo;
psoriasis;
planus;
flebotodermii;
anogenital pruritus;
infected dermatitis (for example, evolved as a result of insect bites).

The drug can be used in children from 1 year.

Dosing regimen

The drug is intended for external use only. Cream or ointment for topical application is applied to the affected area with a thin layer in an amount necessary to cover the surface area, 2 times a day, a little rubbing. At sites with more dense skin (eg elbows, hands and feet) as well as places from which the drug is easily erased, Belogent can be applied more frequently.

Duration of continuous treatment is usually less than 4 weeks. For relapse prevention in the treatment of chronic therapy should continue for some time after the disappearance of all symptoms. During the year, may conduct repeated courses of therapy.

Cream for external use is used for the treatment of acute, including weeping skin lesions.

Ointment for external use is intended for the treatment of subacute and chronic dermatoses, including dry, scaly lesions and lihenizirovannyh.

Side effect

Side effects are generally mild in nature.

Dermatological reactions: seldom - hypersensitivity reactions (itching, burning, redness), aknepodobnye changes, hypopigmentation, striae, skin atrophy, hypertrichosis, telangiectasia. With the development of hypersensitivity reactions or adverse drug reactions should be abolished.

Contraindications
Viral infections of the skin;
skin reactions post-vaccination;
open wounds;
trophic ulcers;
acne vulgaris;
rosacea;
chickenpox;
cutaneous manifestations of syphilis;
lupus;
Hypersensitivity to betamethasone, gentamicin or to any of the supporting components of the drug.

Pregnancy and lactation

Use of the drug in pregnant Belogent possible only in cases where the intended benefits to the mother outweigh the risks to the fetus. In such cases, the use of the drug should be short and possibly beyond small patches of skin.

During the period of breast feeding drug use Belogent possible under strict indications, but the drug should not be applied to the skin of the breast before feeding.

Cautions

Not recommended for long-term use on the face, because may develop rosacea, perioral dermatitis and acne. The drug should not be applied around the eyes, in connection with the probability of getting the drug on the mucosa, which may contribute to the development of cataracts, glaucoma, fungal infections of the eye and exacerbation of HSV infection. Some parts of the body such as armpits, inguinal folds, where there is a natural occlusion, a greater risk of stretch marks, so use of the drug in those areas of the skin should be short.

In cases of fungal flora on the skin, additional use of antifungal agents.

Use in pediatrics

Belogent can be used in children with care and for the shortest period of time. You should not use the drug in children under the bandages and, particularly under the plasticized diapers, because it enhances the absorption of the drug and increases the risk of side effects.

Effects on ability to drive vehicles and management mechanisms

Data on the adverse effects of the drug's ability to operate vehicles and machinery not available.

Overdose

With long-term continuous use of the drug, especially among children, the vast surface of the skin, causing the skin to the tampering with or use under occlusive dressings may develop side effects associated with increased resorption of betamethasone or gentamicin. It should be stressed that the likelihood of such events extremely low.

Treatment: It is recommended to cancel the product and if necessary, appoint a symptomatic therapy.

Drug Interactions

Drug interactions Belogent with other drugs is unknown.

Conditions and terms of

The drug should be stored in a place inaccessible to children at or above 25 ° C. Shelf life - 4 years.