Benfolipen

Release form, composition and packing Benfolipen 

Tablets, film-coated white or nearly white. 1 tab. benfotiamine 100 mg of pyridoxine hydrochloride (vit. B6) 100 mg Cyanocobalamin (vit. B12) 2 mcg. Excipients: karmelloza (carboxymethylcellulose), povidone (Kollidon 30), microcrystalline cellulose, talc, calcium stearate (calcium octadecanoate), polysorbate 80 (Tween 80), sucrose. The composition of the shell: giproloza (hydroxypropylcellulose), macrogol (polyethylene 4000), povidone (polyvinylpyrrolidone low-molecular-medical), titanium dioxide, talc.

Clinico-pharmacological group: Combination of vitamins Group B.

Pharmacological action

Combined multivitamin complex. Effect of the drug determined by the properties of vitamins involved in its composition.

Benfotiamine - soluble form of thiamin (vitamin B1), is involved in conducting nerve impulses.

Pyridoxine hydrochloride (vitamin B6) is involved in the metabolism of proteins, carbohydrates and fats needed for normal blood, the functioning of the central nervous system and peripheral nervous system. Provides synaptic transmission, the braking process in the CNS, is involved in the transport of sphingosine, which is part of the nerve membrane, is involved in the synthesis of catecholamines. Cyanocobalamin (Vitamin B12) is involved in the synthesis of nucleotides is an important factor for normal growth, hematopoiesis, and development of epithelial cells, is required for the metabolism of folic acid and synthesis of myelin.

Pharmacokinetics

Effect of the drug is the combined effect of its components, so the holding of the kinetic observations is not possible, all the components together can not be traced with the help of markers or bio-research.

Statement

It is used in the treatment of these neurological diseases:
trigeminal neuralgia;
neuritis of the facial nerve;
pain caused by spinal cord injuries (including intercostal neuralgia, sciatica, lumbar syndrome, cervical syndrome, cervico-brachial syndrome, radicular syndrome, caused by degenerative changes of spine);
polyneuropathy of different etiologies (diabetic, alcoholic).

Dosing regimen

The drug should be taken after meals, not liquid and squeezed a small amount of liquid. Adults appointed on 1 tab. 1-3 times per day. Course duration - on doctor's advice. Not recommended treatment with high doses of the drug over 4 weeks.

Side effect

Allergic reactions: itching, urticaria rash.

Other: in some cases - increased sweating, nausea, and tachycardia.

Contraindications
severe and acute form of decompensated heart failure;
Infancy;
hypersensitivity to the drug.

Pregnancy and lactation

Benfolipen contains 100 mg of vitamin B6 and therefore during pregnancy and lactation (breastfeeding), the medication is not recommended.

Cautions

During the administration of the drug is not recommended taking multivitamin complexes containing B vitamins

Overdose

Symptoms: increased symptoms of side effects of the drug.

Treatment: gastric lavage, taking activated charcoal, the appointment of symptomatic therapy.

Drug Interactions

Levodopa reduces the effect of therapeutic doses of vitamin B6. Vitamin B12 is not compatible with heavy metal salts. Ethanol dramatically reduces the absorption of thiamine.

Conditions and terms of

The drug should be kept in the dark, dry, place inaccessible to children at a temperature not exceeding 25 ° C. Shelf life - 2 years.