Release form, composition and packing

Ointment 2% homogeneous, white or nearly white. 1 g mupirocin of 20 mg. Other ingredients: polyethylene glycol 400, polyethylene glycol 3350.

Nasal ointment 2%, white or nearly white. 1 g mupirocin of 20 mg. Other ingredients: white soft paraffin, softizan 649.

Clinico-pharmacological group: Antibiotic for local and external use.

Pharmacological action

Broad-spectrum antibiotic for topical and local application. Produced by fermentation of the microorganism Pseudomonas fluorescens. Mupirocin inhibits isoleucyl-transfer RNA synthetase, which leads to the cessation of protein synthesis in the bacterial cell.

Due to the specific mechanism of action and a unique chemical structure, mupirocin does not show cross-resistance with other antibiotics. With adequate application of mupirocin risk of emergence of resistant strains of microorganisms is small.

When used in the minimum inhibitory concentrations of mupirocin bacteriostatic, but in higher concentrations - bactericidal action. In vitro Baktroban active against gram-positive aerobic microorganisms: Staphylococcus aureus (including strains resistant to methicillin and β-lactamase producing), Staphylococcus epidermidis, other coagulase of Staphylococcus, Streptococcus spp.; Gram-negative anaerobic bacteria: Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Branhamella catarrhalis, Pasteurella multocida, Proteus mirabilis, Proteus vulgaris, Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii, Bordetella pertussis. For drug resistant: Corynebacterium spp., Enterobacteriaceae spp., Nonfermentative gram-negative bacillus, Micrococcus spp., As well as anaerobic bacteria.


Absorption of mupirocin through intact skin is low. In the case of absorption through damaged skin mupirocin metabolized to microbiologically inactive metabolite Moniev acid and rapidly excreted by the kidneys.


treatment of primary skin infections: impetigo, folliculitis, furunculosis (including boils ear canal and ear), ecthyma;
treatment of secondary skin infections: infected eczema, infected injuries (abrasions, insect bites), minor (not requiring hospitalization), wounds and burns;
Prevention of bacterial lesions small wounds, cuts and other clean skin lesions, as well as for the prevention of infectious complications of small abrasions, cuts and wounds.

Intranasal ointment
staphylococcal carriage in the nasal cavity (including strains of Staphylococcus aureus, multidrug-resistant and methicillin).

Dosing regimen

The ointment is used topically in adults, children and elderly patients 2-3 times per day. A small amount of ointment applied to affected skin, the top may be bandage. The duration of treatment up to 10 days, depending on performance. In hepatic failure drug is used in the standard recommended dose.

Ointment can not be combined with other drugs for external use because of the risk of dilution, which is manifested reduced antibacterial activity and the potential loss of stability. After applying the product to the skin should be thoroughly wash their hands.

Intranasal ointment is administered in the nasal cavity 2-3 times / day. On the little finger taking a small amount of drug size of a match head and injected into one nostril. Just enter the drug in the other nostril. Then his nostrils shut with two sides, while the ointment is distributed in the nasal passages. The average duration of treatment - 5-7 days. Dosing regimens in children and adults do not differ.

In children and seriously ill patients for the introduction of the ointment can be applied with a cotton swab sticks at the end.

Side effect


Rare: feeling of itching, burning, pain, skin manifestations of allergic reactions at the site of application of ointment.

In isolated cases: systemic allergic reaction.

Intranasal ointment

Probably: rhinitis.

Hypersensitivity to any component of the drug.

Caution should be used during pregnancy and lactation.

Pregnancy and lactation

At present there is insufficient data on the use Baktrobana during pregnancy and lactation. If necessary, use Baktrobana for the treatment of cracked nipples, pacifiers before breastfeeding should be thoroughly cleaned.


Ointment for external use can not be used in ophthalmology, administered intranasally, applied in the field of drainage. Avoid getting the ointment in the eye. If this happens, the eyes should be thoroughly rinsed with water to remove residual ointment.

Polyethylene glycol can be absorbed through the wound surface or via damage to the skin of another kind, in such cases, the polyethylene glycol excreted by the kidneys. Baktroban (like other ointments containing mupirocin, polyethylene glycol-based) can not be used for conditions leading to enhanced absorption of polyethylene glycol, especially for moderate and severe renal insufficiency.

In rare cases of allergic reactions or significant skin irritation at the application of the ointment treatment should be discontinued, the affected area with water to remove residual ointment and appoint an alternative antimicrobial therapy.

As with other antibacterial preparations, prolonged use of ointments Baktroban can lead to excessive growth of non-sensitive microorganisms. Nasal ointment should not be used in ophthalmology.

In the application of nasal ointment should avoid contact with eyes.

Effects on ability to drive vehicles and management mechanisms

Negative impact on ability to drive a car and work with the mechanisms were not observed.


Currently, cases of drug overdose Baktroban were reported.

Drug Interactions

Drug interactions drug Baktroban not described.

Conditions and terms of

The drug should be stored at temperatures not above 25 ° C in the reach of children. Shelf life - 2 years.