Release form, composition and packing Benalgin 

The tablets are round, flat, white, with the dividing line on one side.

1 tab.

metamizol sodium 500 mg.

Caffeine 50 mg.

thiamine hydrochloride, 38.75 mg.

Other ingredients: gelatin, wheat starch, microcrystalline cellulose, colloidal silicon dioxide, talc, magnesium stearate.

Clinico-pharmacological group: analgesic-antipyretic combination composition.

Pharmacological action

Part of the drug metamizol sodium possesses analgesic, antipyretic and anti-inflammatory effects associated with inhibition of prostaglandin synthesis primarily in the central nervous system and increased production of beta-endorphins. Caffeine has some protivomigrenoznoe (tones the blood vessels of the brain) and the stimulating effect: it excites the vasomotor center, promotes efficiency, reduces fatigue and sleepiness. Thiamine hydrochloride (vitamin B1) is involved in the metabolism and enhances neyroreflektornoy regulation.

moderately or weakly expressed pain syndrome (headache, toothache, migraine pain, neuralgia, myalgia, arthralgia, with radicular syndrome, and dysmenorrhea);
for weak pains of visceral origin (renal, biliary colic, spasms of the intestine) in combination with atropinopodobnymi or antispasmodic;
fever with colds and other infectious and inflammatory diseases (at diagnosis).

Usefulness of the drug is solved in each case depending on the severity, nature and portability of a fever.

Dosing regimen

Applied inside after a meal and 1 tablet 2-3 times in the first half of the day. The maximum single adult dose of 2 tablets daily - 6 tablets (not more than 1-2 days). Duration receiving no more than 5 days. Increasing the daily dose or duration of treatment is possible only under medical supervision.

Dosages for children. Children aged 12 to 16 years - half or one tablet 2-3 times per day, maximum daily dose of 4 tablets.

Side effect

At therapeutic doses, the drug is generally well tolerated. Sometimes possible allergic reactions (skin rash, itching, angioedema, rare - anaphylactic shock). With long-term use may breach by the system of blood (thrombocytopenia, leukopenia, agranulocytosis). The propensity to bronchospasm may provoke an attack. There are sleep disturbances, palpitations, cardiac arrhythmias.

Symptoms of acute poisoning: nausea, vomiting, stomach pain, mental and motor agitation, tachycardia, cardiac arrhythmia, possibly reducing urine output, epileptiform convulsions. Should immediately seek medical help. The victim should do a gastric lavage, appoint adsorbents. If necessary, symptomatic treatment.

hypersensitivity to thiamine, caffeine, analgin and other pyrazolone derivatives (phenylbutazone, tribuzon);
expressed in human liver or kidney problems;
genetic absence of glucose-6-phosphate dehydrogenase;
diseases of the blood system;
severe hypertension;
significant signs of atherosclerosis;
intraocular pressure;
during pregnancy and breastfeeding;
Children up to age 12 years;
pregnancy and lactation;
receiving the drug banned.


While taking the drug in the afternoon may be a sleep disorder in the form of sleep disorders.

With caution and under medical supervision to patients with impaired liver or kidney disease.

With long-term (more than a week) use of the drug to be controlled pattern of peripheral blood and liver functional state.

Drug Interactions

The simultaneous use of Analgin with other non-narcotic analgesics, nonsteroidal anti-inflammatory drugs can lead to mutual reinforcement of toxic effects. Tricyclic antidepressants, contraceptives for oral administration, allopurinol violate metabolism analgin in the liver and increases its toxicity. Barbiturates, phenylbutazone and other inducers of liver enzymes reduces the effect of Analgin. The simultaneous use of Analgin with cyclosporine decreases the level of the latter in the blood. Sedatives and tranquilizers increase the analgesic effect of Analgin.

In combination with the above Benalgina and other drugs should consult a doctor and surveillance

Conditions and terms of

Store in a dry and dark place at 15-25 ° C., the reach of children.

Shelf life - 3 years.