Composition, structure and packing

Film-coated tablets 1 tab. extract of K. prostrata ordinary dry 3.2-4.8 mg, which corresponds to 40 mg of medicinal plants.

Excipients: poly (1-vinyl-2-pyrrolidone) (povidone), colloidal anhydrous silica, potato starch, lactose monohydrate, microcrystalline cellulose, magnesium stearate, talc, titanium oxide (E171), iron oxide yellow (E172), lacquer indigotine (E132), macrogol 6000, Poly (Ethyl acrylate, methyl methacrylate, trimethyl-ammonitsetilmetakrilat chloride) 1:2:0.2. Drops for oral administration of 100 g extract of K. prostrata ordinary dry 192-288 mg, which corresponds to 2.4 g of the medicinal plant materials.

Excipients: ethanol content of 17.0 - 19.0 vol.%, Poly (1-vinyl-2-pirolidon) (povidone), sorbitol 70% (noncrystallizing), polysorbate 20, sodium saccharate dihydrate, peppermint flavor, purified water.

Clinico-pharmacological group: herbal remedies, used in the menstrual cycle, mastodynia and premenstrual syndrome.

Pharmacological action

Phitopreparation whose components have a normalizing effect on the levels of sex hormones. Has dopaminergic action that causes a decrease in production of prolactin, ie, eliminates hyperprolactinemia. Increased concentration of prolactin secretion of gonadotropins breaks, as a result of which may cause violations maturation of follicles, ovulation and corpus luteum phase, which further leads to an imbalance between estradiol and progesterone. It is this hormonal imbalance causes menstrual irregularities and mastodynia.

Agnukaston normalizes the ratio of gonadotropic hormones, which leads to the normalization of the second phase of the menstrual cycle. Prolactin also has a direct stimulating effect on proliferative processes in the mammary glands, increasing the formation of connective tissue and causing the expansion of milk ducts. Reduced prolactin content leads to regression pathological processes in the mammary glands and reduces or eliminates the pain syndrome. Pharmacokinetics The action of extract of K. prostrata ordinary is the combined effect of its components, so the holding pharmacokinetic studies is not possible.

menstrual irregularities associated with the lack of corpus luteum;
mammalgia, often associated with pain (mastalgia);
premenstrual syndrome.

Dosage regimen

Assign to 40 drops or 1 tablet. 1 times / day in the morning. The course of treatment - at least 3 months in continuous mode. If, after the withdrawal of the drug complaints appear again, consult with your doctor and continue treatment. Tablets should be taken without chewing. Bottle with drops for oral administration should shake before use, using to keep in an upright position. Side effects Allergic reactions: seldom - skin reactions.

Co of the central nervous system: rarely - psychomotor agitation, confusion, hallucinations.

Hypersensitivity to the drug's components.

Pregnancy and lactation

The drug should not be used during pregnancy and during breastfeeding.


Keep in mind that the drops for oral administration contains 17-19 vol.% Ethanol, so this dosage form should not be applied after successful treatment of chronic alcoholism. Tablets contain the milk sugar (lactose).

Lactose intolerance can be considered as a possible cause of stomach pains and diarrhea, occurring on the background of the drug. Patients should be warned about the need to seek medical advice during the development against the background of the drug weakness, depression, pain in the breasts, menstrual disorders.


In compliance with the recommended dosage regimen of the drug overdose cases were not described. Drug Interactions With simultaneous application of antagonists of dopamine receptors may be mutual weakening of the action.

Drug drug interactions

Agnukaston with other drugs have not been described.

Terms and Conditions of storage

The drug should be stored in a dry place protected from light, at temperatures not above 25 ° C.

Shelf life - 3 years. When storing the drops for oral administration may be a slight loss of sediment that does not affect the effectiveness of the drug.