Composition, structure and packing

Coated tablets light brown, round, biconvex.

1 tab. cytisine 1.5 mg.

Excipients: lactose, microcrystalline cellulose, talc, magnesium stearate, Opadry II.

Clinico-pharmacological group: Drug for treatment of nicotine addiction.

Pharmacological action

H-holinomimetik. Stimulates nicotinic receptors of autonomic ganglia, reflexly stimulates respiratory center, causing the release of adrenaline hromafinnymi medullar cells of the adrenal glands, raises blood pressure.

Reduces nicotine dependence (due to the competitive relationship in the field of the same receptors and biochemical substrates, with which the body interacts nicotine). It changed the taste of smoking (making it unpleasant), reduces the desire to smoke and facilitates manifestation of withdrawal symptoms associated with smoking cessation.

The mechanism of action of cytisine similar to the mechanism of action of nicotine, which makes it possible to phase out smoking at the same time prevents the development of abstinence phenomena.


Data on pharmacokinetics is not available.

Nicotine addiction (to facilitate smoking cessation).

Dosage regimen

The drug is prescribed for 3 days to 1 tab. 6 times / day (2 h) in parallel reduce the number of cigarettes smoked. In the absence of the effect of the drug should be removed and after 2-3 months to begin a new course.

With the positive result of treatment should be continued as follows:

Frequency of treatment / Multiplicity / receiving dose

from 4 to 12 days to 1 tab. every 2.5 h 5 pi.

from 13 to 16 days for 1 tab. every 3 h 4 pi.

from 17 to 20 days to 1 tab. every 5 h 3 pi.

from 21 to 25 days to 1 tab. every 6-8 hours 1-2 tab.

Smoking should be discontinued no later than 5 days from start of treatment.

Side effect

On the part of the digestive system: changing tastes and appetite, dry mouth, abdominal pain, nausea, constipation, diarrhea.

From the side of the central nervous system: headache, dizziness, insomnia, drowsiness, increased irritability.

Since the cardiovascular system: a feeling of palpitations, a slight increase in blood pressure, tachycardia, chest pain, shortness of breath.

Other: myalgia, weight loss, increased sweating, allergic reactions.

Most adverse events are held independently.

Acute myocardial infarction;
unstable angina
recently transferred cerebral blood flow;
marked atherosclerosis;
bleeding from large vessels;
pulmonary edema;
peptic ulcer of the stomach and duodenum (phase exacerbation);
lactation (breastfeeding);
Hypersensitivity to the drug.

With care prescribers in schizophrenia, hromafinnyh adrenal tumors, gastroesophageal reflux, with coronary artery disease (including chronic heart failure), cerebrovascular disease, hyperthyroidism, peptic gastric ulcers, diabetes, renal and hepatic failure. Children under the age of 18 years and patients older than 65 years the drug should be used after careful evaluation of the ratio expected benefits and potential risks.

Pregnancy and lactation

Do not assign Tabex during pregnancy because of the potential risk of embryotoxicity in uncontrolled admission.

Do not take the drug during lactation (breastfeeding).

Application for violations of liver function

Be wary prescribers with hepatic failure.

Application for violations of renal function

With care prescribers in renal failure.


The drug should be used only if the patient has a serious and deliberate intention to quit smoking.

The patient should be warned that the use of the drug on the background of continued smoking can lead to nicotine poisoning.

Effects on ability to drive vehicles and management mechanisms

Acceptance of the drug did not cause changes in mental and physical condition of the patient, does not violate the ability to manage road and work with mechanisms.


Symptoms: nausea, vomiting, dilated pupils, weakness, tachycardia, convulsions, respiratory paralysis.

Treatment: gastric lavage, control heart rate, blood pressure, respiratory function, if necessary - the introduction of infusion solutions, anticonvulsive drugs, cardiac, analeptic and other symptomatic means.

Drug Interactions

The drug should not be used simultaneously with anti-TB drugs.

Terms and Conditions of storage

The drug should be stored in a dry place protected from light, away from children at or above 25 ° C. Shelf life - 2 years.