Composition, structure and packing Ibalgin 

The cream for external use only 5% of the emulsion type, white or nearly white.
1 g of ibuprofen, 50 mg

Excipients: vitepsol (hydrogenated fat), medium saturated triatsetilglitseridy (migliol 812), tsetilstearilovy alcohol, Ethoxylated alcohols, C12-C16 (slovasol 2430), monoglycerides of saturated fatty acids (polinol A), Carbomer 940, trolamin, methylparaben, propylparaben, propylene glycol , purified water.

Clinico-pharmacological group: NSAID for topical use

Pharmacological action and pharmacokinetics Ibalgin 
Anti-inflammatory, analgesic, antipyretic. Selectively inhibit cyclooxygenase 2 isoenzyme

Maximum concentration is created through 0,5-1 hours

Slowly penetrates into the joint cavity, but is retained in the synovial tissue, making it more concentrated than in plasma. Biotransformation.

We derive the kidneys. Anti-inflammatory effect is associated with a decrease in the permeability of blood vessels, improving microcirculation, decrease the release of inflammatory mediators from the cells and the suppression of energy of the inflammatory process.

Analgesic effect is due to decrease in intensity of inflammation, reduced production of bradykinin and its algogennosti.

The decrease in excitability teploreguliruyuschih centers diencephalon incur antipyretic effect.

In single dose effect lasts up to 8 hours

It has antipyretic effect, the severity of which depends on the initial body temperature and dose. Reversible inhibition of platelet aggregation.

rheumatoid arthritis
reactive synovitis with deforming osteoarthrosis,
psoriatic arthritis
acute articular gouty attack,
ankylosing spondylitis (Bechterew's disease),
cervical spondylosis,
Barre syndrome - Leu (cervical migraine
vertebral artery syndrome),
Thoracic radicular syndrome,
neurovegetative amyotrophy,
occipital and intercostal neuralgia,
pain in the surgical wound,
surgery in the oral cavity,
inflammatory processes in the small pelvis,
postural hypotension while taking antihypertensive
nephrotic syndrome (to reduce the severity of proteinuria).

Dosage regimen Ibalgin 

Outwardly. Strips of cream 5-10 cm length is applied to the affected area thoroughly and rub lightly until fully absorbed 3-4 times a day for 2-3 weeks.

Side effect Ibalgin 

Dyspeptic disorders (nausea, heartburn, anorexia, vomiting, discomfort in the epigastric region, flatulence, diarrhea, obstipatsiya), erosive and ulcerative lesions with gastrointestinal symptoms of gastrointestinal bleeding, headache, dizziness, tinnitus, insomnia, agitation, visual impairment (blurring of vision, color vision changes), fluid retention, edema, high blood pressure, thrombocytopenia, granulocytopenia, hemolytic anemia, Quincke's edema, bronchial obstruction, allergic skin reactions.

stomach ulcer and duodenal ulcer in acute,
ulcerative colitis
"Aspirin" asthma
leukopenia, thrombocytopenia,
hemorrhagic diathesis,
severe dysfunction of liver and kidney,
portal hypertension
heart failure
disease of the optic nerve,
of color vision,

Pregnancy and lactation

Acceptance of the drug is contraindicated.


Given the possibility of developing NSAID-gastropathy, with care appoint the elderly with a history of stomach ulcers and other digestive diseases, gastrointestinal bleeding, while glucocorticoid therapy, other NSAIDs for long-term therapy. If you have symptoms of gastropathy shows careful control (including an esophagogastroduodenoscopy, analysis of blood hemoglobin, hematocrit, and analysis of occult blood). To prevent the development of NSAID-gastropathy should be combined with drugs PGE (misoprostol). With care administered in childhood (12 years), patients with severely impaired liver function and kidney (required regular monitoring of bilirubin, transaminases, creatinine concentration capacity of the kidneys), hypertension and chronic heart failure (daily monitoring of urine output, body weight , blood pressure). When a visual impairment should reduce the dose or repeal the drug. Avoid drinking alcoholic beverages during the treatment.


Symptoms: abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, coma, acute renal failure, hypotension, bradycardia, tachycardia, atrial fibrillation and respiratory arrest.

Treatment: gastric lavage (only during the first hours after admission), activated charcoal (to reduce absorption), alkaline drinking, forced diuresis and symptomatic therapy (correction of acid-base balance, blood pressure, gastro-intestinal bleeding).

Drug Interactions Ibalgin 

Decreases antihypertensive activity of ACE inhibitors, natriuretic - furosemide and hypothiazide.

It may increase the toxicity of methotrexate and lithium preparations.

With the combined use of anticoagulants cumarine type and alcohol increases the risk of hemorrhagic complications, with tablets glucocorticoids - risk of gastrointestinal bleeding.

Not recommended for use simultaneously with acetylsalicylic acid or other NSAIDs, antidiabetic drugs, phenytoin and hormonal contraceptives.

Increases the concentration of digoxin in plasma. Caffeine increases the analgesic effect of ibuprofen.

Terms and Conditions of storage

In a dry place at a temperature of 10-25 ° C.

Shelf life - 2 years.