2010/06/14

Permethrin

International name:
Permethrin (Permethrin)

Group Affiliation:
Insecticide

Description of the active substance (INN):
Permethrin

Mode of action:
Antiparasitic products, has protivopedikuleznoe, insecticidal action. Violates the permeability of Na +-channels of membranes of nerve cells of insects, inhibits the process of polarization (repolarization) of the nerve cell, which leads to paralyzing effect. It is effective against nits, larvae and mature specimens of head and pubic lice, fleas, ticks (including scabies), and others of the family of ectoparasites of arthropods. With a single treatment of the surfaces affected by head lice, the action is saved from 2-3 weeks to 6 weeks (depending on your dosage form). As antiscabious drug is effective after a single procedure. Low toxicity to humans and when applied to the skin in recommended doses and concentrations, has no skin-resorptive, local irritating and sensitizing effects.

Indications:
Pediculosis of the scalp, pubic lice (including gnidonositelstvo). Scabies.

Contraindications:
Hypersensitivity, acute inflammatory diseases of the skin of the scalp, the period laktatsii.C caution. Pregnancy.

Adverse effects:
Allergic reactions: skin rash, swelling. Local reaction: burning skin, paresthesia, increased pruritus, erythematous rash.

Dosage and administration:
Hair richly moisturize solution with a cotton swab, rubbing the drug in hair roots. Cost per person - 10-60 ml, depending on the thickness and length of hair. After processing the kerchief covering his head, and after 40 min drug wash off with warm running water with soap or shampoo. After washing your hair, comb comb to remove dead insects. If live lice are found after 7 days after the application of the drug, recommended re-treatment. If you have any danger of re-infection in a group (school, kindergarten) to use drugs after washing the head and leave it on the hair after drying. The damage to the hair drug maintains its activity for approximately 2 weeks (due to breed again had fallen to the hair lice). Repeat treatment after each hair wash. Dead nits are removed from the hair or a thick ridge on one since they are firmly fastened to the hair. Cream. When scabies 5% cream carefully rubbing massaged into the skin of the head to the soles of the feet - both adults and children, the children must treat the scalp, temples and forehead area, for the treatment of adult patient enough in 1930 after 8-14 h after treatment cream be washed off. If you have a permanent itch after the treatment 14 days later to repeat the process. Solution. A bottle containing 24 mL of the drug, intended for a three-day course of treatment. For ease of use are printed on the vial label. Applied externally in the form of freshly prepared 0.4% aqueous emulsion, for which 1 / 3 the contents of the vial (8 ml) is added to 100 ml of water at room temperature. The finished emulsion 1 times a day (at night) carefully rub on the skin of the upper extremities, trunk, and then the lower limbs. Do not be processed skin of the face and neck, and scalp. At the end of treatment on the fourth day the patient should take a shower and a change of underwear and bed linen.

Cautions:
Treatment is carried out in a well ventilated area or outdoors. Avoid application to mucous membranes of the eyes, nasal passages, oral cavity and external genitalia, the processing can be protected with a cotton swab (in case of accidental exposure, they should be rinsed in running water). After treatment should be washed hands and rinse mouth with running water. In case of ingestion, gastric lavage should be, and symptomatic therapy.