Release form, composition and packing Basiron AC
Gel for external use only 2.5% of 1 g of benzoyl peroxide 25 mg. Other ingredients: acrylate copolymer, poloxamer 182, carbomer 940 (carbopol 980), glycerin, disodium edetate, sodium dioctyl sulfosuccinate, propylene glycol, silica colloidal anhydrous, sodium hydroxide, distilled water.
Gel for external use only 5% of 1 g of benzoyl peroxide 50 mg. Other ingredients: acrylate copolymer, poloxamer 182, carbomer 940 (carbopol 980), glycerin, disodium edetate, sodium dioctyl sulfosuccinate, propylene glycol, silica colloidal anhydrous, sodium hydroxide, distilled water.
Gel for external use only 10% of 1 g benzoyl peroxide, 100 mg. Other ingredients: acrylate copolymer, poloxamer 182, carbomer 940 (carbopol 980), glycerin, disodium edetate, sodium dioctyl sulfosuccinate, propylene glycol, silica colloidal anhydrous, sodium hydroxide, distilled water.
Clinico-pharmacological group: Drug for the treatment of acne.
The drug has high antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis, has komedonoliticheskoe and anti-inflammatory effect, improves oxygenation of tissues, suppresses production of sebum in the sebaceous glands, absorbs excess sebaceous secretions and moisturizes the skin. Benzoyl peroxide, being a powerful oxidizing agent, has a strong bactericidal effect on microorganisms, with micro-organisms are not able to develop resistance to benzoyl peroxide strains. In in vivo studies on the results of seeding, it was shown that the inhibition of culture growth Propionibacterium acnes by 94% observed at the 7 th day and 15-day - at 97-99%.
Anti-inflammatory effect benzoyl peroxide based on the inactivation of free radicals in the inflammation and inhibition of free fatty acids. Basis of preparation before the complex acrylate copolymer / glycerin, it provides a controlled adsorption of excess sebum and gradual release of glycerin to soften and moisturize the skin.
Most of benzoyl peroxide biotransformed into benzoic acid (95%) in the human skin; unchanged benzoic acid is rapidly excreted in the urine. Data accumulation in the tissues there. In preparation revealed no systemic action.
The drug should be applied to clean and dry surface of affected skin areas 1 or 2 times a day (morning or evening). The course of treatment - 3 months. Therapeutic effect develops within 4 weeks after the start of treatment.
Sustained improvement comes after 3 months of therapy. Baziron AU is indicated for the treatment of acne is mild to moderate severity with the prevalence of pustular elements as a single agent, while moderate acne in combination with other local (retinoids) and systemic (antibiotics, antiandrogens for ingestion). If necessary, may conduct re-treatment.
Rare: skin irritation at the site of application of the drug, dry skin, allergic reactions. There is no data on the development of systemic side effects when applied externally drug Baziron AU at the recommended doses.
Children up to age 12 years;
hypersensitivity to the drug.
Pregnancy and lactation
It is not recommended to use the drug Baziron AU during pregnancy and lactation.
When a skin irritation after applying the gel Baziron AU should be abolished. Do not apply the gel on the skin to damage the integrity of the skin.
In case of accidental contact with the drug on the mucous membrane of eyes, mouth or nose, you should thoroughly rinse it with warm water. During the period of the drug should avoid exposure to the field of its application to direct sunlight, since it can cause skin irritation.
During the period of Bazirona AU is not recommended the simultaneous use of Dries up oily or irritating (or spirits etanolsoderzhaschie means).
Symptoms: When a random drawing of a large quantity of the drug on the skin may cause strong irritation at the site of application.
Treatment: The drug should be discontinued and symptomatic treatment.
Data on drug interactions drug Baziron AU applied for indications and recommended doses, other drugs for topical and systemic application is currently unavailable.
Conditions and terms of
The drug should be stored at temperatures not above 25 ° C. Shelf life - 3 years.